Project leaders: Sébastien MERIAUX , Sandy PAYAN , Sandra PREVERAL
For diagnosis and therapy - (20/03/2025)
Magnetosomes (MTs) are magnetic nanostructures of bacterial origin composed of an iron oxide core surrounded by a proteo-lipid membrane. They are biocompatible biological contrast agents that surpass synthetic nanoparticles in terms of MRI contrast agents. The aim of the project is the early detection of tumours. Thanks to their natural membrane, MTs can also be functionalised with ligands, genetically or chemically, to specifically target tumour cells or vectorise pharmaceuticals while sparing healthy tissue. The project is currently in the technological maturation phase, with the aim of adapting these biomaterials to the regulatory and industrial requirements associated with drug development.
Contact : Sébastien MERIAUX (CEA Neurospin, CIEL laboratory) – Sandy PAYAN, Sandra PREVERAL (CEA Cadarache, BIAM team)
