18F-FDG PET imaging, an indicator of cerebral metabolism, reveals variations in glucose metabolism across brain regions in mice exposed to tobacco. This mouse model of tobacco exposure, combined with 18F-FDG PET imaging, provides a robust preclinical platform for testing innovative smoking cessation strategies.
This case study stems from work by Nicolas Tournier’s team at SHFJ / CEA, published in the journal ACS Chemical Neuroscience, on the central mechanism of action of NFL-101 in the fight against tobacco addiction.